President: In order for Clinton to lose Illinois, she would have to lose by large numbers nationwide. In fact, she would probably have an opponent with over 400 electoral votes. There is no intication that will even be within the realm of possibilities.
Senate: Here we have a much more competitive race. This race has gotten even more competitive due to the "loose cannon" Kirk has become. His recent comments about driving faster through black communities and Senator Graham being a "bro with no ho" will not do him any favors. He has also drawn probably the most difficult opponent he was likely to face in Tammy Duckworth.
The only polling for this race we have is a We Ask America poll from last December which gives Duckworth a lead of less than 1%. If anything, the outlook of this race is a lean-Dem pickup for 2016. While Kirk could still rebound, it seems more likely than not that Kirk will be one of the most vulnerable Republican Senators up for reelection in 2016.