The Senate race here is Lisa Murkowski running for reelection. In 2016, she lost in the primary to Joe Miller. Despite that, she went won to win a three way race while running as a write-in candidate. It is unclear whether Murkowski will face Miller for another challenge from the right in 2016. The Democrats best chance here is if she gets primaried out or faces a strong third party and a strong opponent runs. The strongest opponent would be former Senator Mark Begich. Murkowski turned on her colleague and endorsed Sullivan in 2014, which irked Democrats and some Independents in the state. She has never been very popular with Republicans. Her only positive approval rating has been with Democrats. With her turning her back on them in 2014, she might be hard pressed to find much love here. That being said, he biggest threat is primarially within her own party.
Another seat up for grabs here is Alaska's only House seat. Don Young, who will be 83 in November 2016, will likley run for reelection. He has said numerous things over the years that have not at well with many in the state. Most recently, his comments about suicide. He could face Mark Begich (should Begich not run for the Senate) or a number of State Senators.
This state is unlikely to turn blue for the Presidential race. Both the Senate and House races would have to turn blue before Clinton would win here. That being said. Alaska is only of the few states that Obama did better in in the 2012 election than he did in the 2014 election. PPP is the only firm to test these numbers. They found Clinton losing in mid-single digits with a 2014 mid-term electorate. That will likley be the case unless the GOP nominates a disaster or the Senate and House races really go south for the GOP. Even so, I wouldn't could on this one being anything but a single digit GOP victory in 2016.